Showing posts with label ovidrel. Show all posts
Showing posts with label ovidrel. Show all posts

Saturday, December 27, 2014

The Official Start of my IVF Cycle

Ahhhh the time has come, it's the OFFICIAL start of my upcoming IVF cycle. What starts the cycle, you ask? Birth control pills!! Hahaha, so funny, right? Did you know that a typical IVF cycle is 6 weeks?! Gosh that feels like such a long time haha, I kind of just want to fast forward ahead to February! LOL. No, it's all worth it of course :D So I started my pack of birth control pills tonight and have received my official calendar.

The course of events is as follows:
12/27 -- Start birth control pills
1/1 -- Call insurance to activate IVF coverage
1/2 -- Mock transfer
1/12 -- Start Lupron (1st injectible medicine)
1/16 -- Last active birth control pill
1/19 -- Baseline blood work and ultrasound
1/23 -- Start the injectible medicine to stimulate my ovaries to grow follices (Follistim)
1/26 -- Blood work to check estradiol levels
Week of 1/26 -- more blood work & ultrasounds
Week of 2/2 -- more blood work & ultrasounds; then when my follicles are the appropriate size we will stimulate ovulation (ovidrel) then have the egg retrieval!
5-7 days after egg retrieval is the embryo transfer -- the plan is to transfer 2 embryos
Then we WAIT! AHHHH!!!

I'm really excited but I'm also super nervous as well. We've never had many great embryos in the past so this makes me nervous, all it takes is one though (Hello, Mr Hank <3)!! So hoping for more embryos this time, would even be nice to have some to freeze. IVF is a very emotional process, so I'm not really looking forward to that. And last time I didn't have a toddler running around keeping me busy too so I'm sure I'm going to be extra tired. I always make sure to schedule the earliest appointments so I can get back to work so I don't have to use any time. So that means leaving my house around 6 am (yuck!). So that'll be hectic with daycare and what not too. Normally I take Hank to daycare at 8 am, but Casey will have to take him before he goes to work on days that I have monitoring up in Buffalo, so he'll have to go at probably 7:15 am to give Casey time to get to work. So I think we'll all be tired for that couple of weeks there! Keeping the end goal in sight will definitely help us all! I am so excited to hopefully give Hank a little brother or sister!! :D Keep us in your thoughts & prayers please over the next 2 months, we will really appreciate it!!

Thursday, August 23, 2012

Twas the Night Before Egg Retrieval

Twas the Night Before Egg Retrieval...

Tomorrow is my egg retrieval and I'd be lying if I said I wasn't nervous. I'm just as nervous this time, if not more nervous, than I was last time. I also never imagined I'd be doing this again so soon as in my mind, I should be 6 months pregnant right. However, I'm not, so here I am going through all this to TRY to get my baby. 

Last night at 8:30 pm, I triggered ovulation with Ovidrel. I bled a little, no big deal. After the shot, it instantly became real and I started worrying...did I do that shot right?! Of course I did, it's really the only shot you CANNOT mess up! It's a pre-filled syringe, you stick it in and inject the solution. That's it, nothing you can mess up. Okay, so ovulation will now occur 36 hours later...how does it know to ovulate me 36 hours later? I've always wondered that, what if it ovulates sooner? This is what starts running through my head and this is just the beginning. 

Today I've been pretty nervous about tomorrow. The unexpectedness of last cycle started coming into my head which leads to the unexpected of this cycle. Last time, we expected to get 12 eggs, only got 7, only 3 fertilized, only 1 was viable which led to a 2 day transfer. It did lead to a pregnancy, so I know it only takes one, but that was the scariest thing to go through all the drugs, all the ultrasounds, all the injections and wondering if I would even make it to embryo transfer. I know where the nerves come from, I'm sure it happens to everyone but knowing what can happen, some don't even make it to embryo transfer, that's what makes me so nervous.

It's the "unknown," I wish I could some how know exactly what was going to happen. So here I am, figured I'd write a quick post before I relax for the rest of the night. Casey and I went to Bob Evans (haha we act like we're 60 years old at times) and it was damn good! I took my doxycyline and so far it hasn't made me feel like shit, and I've used the (TMI!!) medicated douche my doctor told me to use (EWW I feel so violated right now haha), but I'll do whatever I need to do. 

Here's what this cycle has consisted of: 

  • 1 Mock Embryo Transfer
  • 21 days of birth control pills
  • 23 days of the Lupron injection
  • 12 days of Follistim (FSH) injection & SolX (LH) injection
  • 1 Ovidrel ovulation shot
  • 9 trips to Buffalo IVF at 52 miles each way
  • 8 blood work draws
  • 6 vaginal ultrasounds
In case you didn't know, that's what it takes just to get to tomorrow, egg retrieval. There is so much invested and now I enter the world of the unknown. How many eggs will they retrieve? How will I feel? Will I be in much pain after? Will the IV hurt going on? How many eggs will fertilize? How will the quality be of the embryos? How many embryos will make it to transfer day? WILL THIS WORK?!

Please be thinking and praying for us tomorrow and going forward for hopefully the next 9 months! <3

Wednesday, August 22, 2012

After final stims

After stimming for 12 days, follies are ready! Dr measured 8 on my right side (there were a few more he didn't measure) & 5 on my left side. A few more woke up since Tuesday morning yay! We're officially ready to go for ER on Friday morning!! Triggering with ovidrel tonight!

Friday, January 13, 2012

The Road to IVF

So we had our consultation with Dr. Sullivan on Thursday (1/12), it went really good but of course I always think of one million questions after I meet. Anyways, I found this really great website that explains the whole IVF process from me starting a new cycle to hopefully finding out that it worked. The article is called Understanding IVF Treatment Step by Step. It's helped me understand things a little better but I think I still need to make a phone call to talk to the IVF nurse to answer a few more questions.

Our percentage of IVF working is even greater than IUI, so I really hope it is successful...IVF is going to be the beginning of an end of an era for us, whether it works or not. I am of course still very hopeful that I'll be able to have my own children. One of the things we took from the meeting was that our percentage of having twins is now 50%!! This is super exciting for us. Within days of dating, Casey and I both talked about wanting twins. It's just something we've both always wanted. So maybe the reason we have to go through all of this is to get our twins...who knows. Of course we would be ecstatic to get one baby, but we'll be excited if we get two as well! Anyways, after all the scientific talk and what drugs I'll be taking and what not, Dr. S. talked about how well I've responded to the Follistim in the past (ie the reason we had to cancel the current cycle - I responded too well for IUI), so he thinks he'll be able to get 10 good oocytes out of me and about 70% will likely become embryo's. Dr. S. will transfer 2 embryo's into my uterus. This could leave 5 healthy embryo's leftover which will be frozen for possible future use. So if this IVF doesn't work or if we decide to have more children in the future, we don't have to go through all the hassle we've gone through this time. I would just have my body "tricked" again then when the time is right, embryo's would be transferred in. If we decide not to use them, we can have them destroyed, can give them to someone else we identify within the practice (huge hassle though as he pointed out, plus I don't know if I could let someone else have "our children"), or they can be donated to research which would be ideal for us if we don't use them.

Once I start my new cycle, I'll get started on birth control and then Lupron to trick my pituitary gland. Essentially, the doctor will have total control over my reproductive system. The meds he gives me tells my body what to do and when. Pretty crazy how we can take control over our bodies! Then I'll be back on Follistim and a new drug for me called Ganirelix. Then once Dr says it's time, I'll take the Ovidrel shot and have the egg retrieval done 36 hours later!! I'll get an IV of "Michael Jackson's favorite drug" Propofol (don't worry, it's a very safe form of an anesthetic when given safely and as prescribed) to put me to "sleep" while they retrieve the eggs. I'll then add another drug in there after retrieval (can't remember the name of that one right now)...this is a lot to remember!! Lol. Then, 3 days after egg retrieval, he will transfer 2 embryo's into my uterus. So after the embryo's are transferred, I will start the daily Progesterone (brand name endometrin) and have the dreaded two week wait to see if it worked. So stay tuned, this is a fairly long process. So that's what IVF is in a nutshell, the link above probably does a better job at explaining it than I have, but that's where we're at...

To end, in 7 days and 10 hours, we will be on that big bird to Las Vegas!! :-)

Friday, January 6, 2012

Happy New Year!

So I realize it's been awhile since I've done a new post about our journey, so I'm finally sitting down and writing one.

When I last posted, we were in a month of trying to get pregnant "the old fashioned" way ;) Well I got excited that cycle because it was longer than normal, I ended up going to Buffalo for a pregnancy blood test on a Saturday, thereby not receiving results until Sunday. I got a phone call Sunday morning that it was negative, and hours later my cycle started...hence, my body hates me! If only I'd waited another day, I would have saved myself the copay, gas money, and time to get a test I didn't need.

My next cycle, I went back to the treatment pre-surgery. I started out on the Femara pill, then took the Follistim shot, then the Ovidrel shot 36 hours before insemination. Since Casey is now laid off, he came to the insemination with me. That same morning, a fellow infertile friend had an insemination. I asked her how it went on my way to my appointment, and she told me that her's was horrid! She said it was very painful and that the nurse was very rough with her. I asked her to describe the nurse to me and it happened to be the same nurse that I once had and had a painful insemination with. Inseminations are not meant to be painful, they can be uncomfortable at times, but definitely should not be painful. As Casey and I waited in the waiting room, after 30-45 minutes (very unusual wait time), we were called back by that same nurse. My stomach instantly sank and I became very nervous. I was almost in tears knowing that she'd be doing my insemination. Well before the insemination, they do an ultrasound. This was a very uncomfortable ultrasound (which normally they are not), which made me even more nervous for my insemination. The insemination was long and painful. When it was time to leave, Casey talked to a fellow nurse and asked if there was anyway that I could chose to not have her again. It's not something they can put in our file (which is understandable) but when we checkin we can request to have a specific nurse or request to not have a specific nurse, thankfully. I'm already emotional about this whole thing, I need to be as comfortable as possible when having a catheter inserted!! I know most people would agree here!! Anyways, unfortunately a new cycle started two days after Christmas. Thankfully the day it started, I had plans to do lunch and shopping with a friend. That definitely helped get my mind off things for a bit. Thanks Lindsay! :-) Anything to take my mind off starting a new cycle is a good thing!!

So we're doing one more cycle of the same combination Femara, Follistim, Ovidrel and IUI. They've upped by dosage of Follistim this time, so hopefully that'll help! I've been monitored via bloodwork which checks the Estrogen levels. Ohh and I've given myself every single Follistim and Ovidrel shot in the last 2 cycles, go me!! (I guess it's not necessarily a good thing I'm getting good at these). The one I gave myself tonight kinda hurt, and so did last nights! I think the skin gets a little tender after a few days of the shots. So I have bloodwork tomorrow morning (Saturday) and I'm assuming I'll go back into the office on Sunday or Monday for bloodwork and ultrasound. I'm guessing my IUI will be somewhere between Tuesday and Thursday, my guess is it'll be Wednesday. Then we'll wait and see what happens.

In the meantime, on Thursday January 12, we have an IVF consultation with Dr. Sullivan. IVF is also known as In Vitro Fertilization. This will likely be the last thing we do to hopefully beat infertility. It is considered to be the most expensive and most intensive infertility procedure. My guess is that if this cycle's IUI is not successful, we will begin IVF. I don't know a whole lot about IVF, I mean I know they take my eggs and Casey's sperm and put them together to make an embryo and then insert 1-4 back into my uterus, but I'm not sure what meds I'll be on and how often I'll have to be monitored. I'm assuming the meds will be like the ones I'm on now, but my guess is I'll have to be monitored closer, therefore more ultrasounds and more bloodwork. I've found a couple links that describe the IVF process and it is very interesting. I'm really hoping it works. At least doing all this, I'll know that I've done everything possible to conceive my own child, and hopefully I'll have the piece of mind knowing that I did what I could do. One link I found is through the American Pregnancy Association it basically explains IVF in "Layman's" terms. Another link I found is a Youtube video that's a 3D animation of how IVF works.


So that's what's been going on with us! I'm still hopeful that we will get pregnant.

Onto fun stuff, we're going to Vegas January 21 through 28th, I absolutely cannot wait!! We definitely need a vacation to get away and to get things off our mind!! I really hope that Vegas will bring us some good luck!! Casey plans on doing some gambling, I might play a couple slot machines but that's about it! I'm more interested in seeing everything and shopping!! I can't wait to see all the ritzy stores that I dream about! :-) We will be taking a day to go to the Grand Canyon Skywalk, I've heard that it's breathtaking, I cannot wait to step foot onto the Skywalk and look down! Haha! And take tons and tons of pictures and use my new Flip video camera!! We're also going to visit the Hoover Dam as well. Hopefully we'll see a couple shows as well! I know that it'll be a busy week, but I can't wait!!

I'm still selling Miche Bags and loving it!! Definitely a great thing to get my mind off things and have some extra fun! I got a new website which is pretty awesome, check out My Website! Feel free to shop around and let me know if you have any questions! I'm looking for parties. I want to share the word on how awesome this product is! :-)

Anyways, thanks to everyone who's reading and offering their support. Since I've started writing my blog, I've received support from people I didn't realize I'd receive support from and it's been great! Writing has definitely helped me to express everything I'm feeling emotionally and to just get it out there! So Thank You!! :-) Happy New Year!

Saturday, October 8, 2011

What I have been through since July 15, 2010

So, my original purpose for starting a blog was documenting what I was going through while pregnant. I have yet to become pregnant, and it just occurred to me that I could blog what I'm going through while trying to become pregnant. If/when I ever do become pregnant, I know it will be nice to have this blog to look back on to reflect what I went through, and possibly for my child to read one day to see what I had to go through to have them.

On July 15, 2010, Casey and I decided to start trying for a baby. At this time, I was working as a tax accountant, so we decided we would start trying once tax season would be over if I were to get pregnant at that time. So I started my cycle not long after that. At this point in time, my cycles were quite long, approximately 40 days. I had been keeping track of my cycles using an app on my iPod, so it calculated when I should be ovulating and when I should get my period. Well I was due for my period while vacationing in OBX, so I brought pregnancy tests with me, I thought how cool would it be to find out I'm pregnant while on vacation...that was my first negative pregnancy test in this journey.

To back track a few years...back in 2007, my cycles started getting longer and longer, and I was straight-up skipping periods, I was not on birth control because it never reacted well with my body. I decided I should look into this since I knew it was not right, I went close to 3 months without a period. I started going to a doctor who started testing me for everything! I had so many blood tests run, and had ultrasounds, everything! By a process of elimination, the doctor said I have PCOS. I do not "look" PCOS --> most women with it are overweight, have excessive body hair, and many other qualities you can see. The only thing the doctor could "see" were more than normal cysts on my ovaries, so they say this is what I have. Many people never have problems getting pregnant with this, and many people do. The doctor started me on a medication called Metformin. This medication has helped me have a more "normal" cycle. I've been on this medicine every since, and last fall my dosage was increased, I have to take 2 pills every morning and 2 when I go to sleep.

Back to reality, I started going to a Gyno in September, 2010. She saw all of my past information, had me do tons of blood tests and instead of wasting time, she decided to start me on your "basic" infertility medicine. This medicine is called Clomid. I take it for cycle days 3-7, then normally around day 14 which is about when one should ovulate, I'd go into the doctor's office for an ultrasound of my ovaries. At this time, they would look at both ovaries, and measure the size of the growing follicles which in turn release the egg. It didn't look great for the first cycle on Clomid. So we decided to try it again for my next 4 cycles (it's only safe to take for a total of 6 cycles). Unfortunately, I was not responding to Clomid like they had expected, so my next step was to see an infertility doctor.

On March 1, 2011, Casey and I had our first meeting with Dr. Sullivan at Buffalo IVF. He asked us a bunch of questions, looked at all of our past history, and decided to start me on a fertility medicine that women normally respond to if they don't respond to Clomid. This is also the day that we found out that Hopper was doing very bad, the cancer was eating him from the inside out. As we were taking the next steps to welcome (hopefully) a new life into this world, we had to make the decision to put Hopper down the next day (P.S. I'm crying right now as I'm writing this, just thinking about this, we loved him so much!). Before Dr. Sullivan started me on anything, he wanted to make sure that my tubes were clear and looked good, so I had to have a procedure done called an HSG (or dye) test, where a catheter is inserted into the Uterus and then dye is flushed through the tubes to check for any blockages, which I had none, so good news. P.S. Having a catheter inserted into the Uterus hurts like hell, it feels like a contraction, the Uterus does not like things inserted into it!

Okay, so the new med that Dr. Sullivan started me on is called Femara, it's actually used to treat breast cancer in women, but is used highly by infertility doctors. I started on Femara in April after a long March cycle. Femara is an oral medication, taken like Clomid, days 3-7. After an unsuccessful cycle on this, we decided to introduce the next step, which is getting an IUI (or intrauterine insemination or artificial insemination).

I took the Femara on days 3-7, then I started getting my ovaries/follicles measured by ultrasound on Day 10, and continued until they reached a certain size. For my first insemination, I had a follicle that measured 21 mm, which is a good size for insemination. Being this size means, it should be ready to be released and I will ovulate (hopefully). I decided to take an at-home pregnancy test 2 weeks after that, which was negative. So after yet another unsuccessful cycle, we decided to introduce one more thing that should help.

In June, I took the Femara on days 3-7, started getting my ovaries/follicles measured around Day 10, and on Day 13 I took the new drug, Ovidrel. Ovidrel is given by shot in the abdominal area (no it doesn't hurt). This is done at home around 8 pm, then 36 hours later, an IUI is done at the doctor's office. When I first found out I'd have to take a shot, it made me nervous, but then I wondered how I was going to get this shot. I did not think Casey could give it to me because he HATES shots, needles, bloodwork, all that. I mentioned to him about contacting a nurse friend and he said "I can give it to you," he doesn't have a problem administering shots, he just doesn't like to receive them. So, he gave me my Ovidrel shot which induces/pinpoints ovulation, and then I had my IUI on Day 15. In case you are wondering, the IUI does not in any way replace Sex! It's just another way that could assist in getting pregnant because the sperm is injected directly into uterus, and doesn't have to travel. P.S. Casey has "super sperm," so in case you were wondering again, I am the only problem, thankfully he is not. I think he could look at someone and knock them up with how many active sperm he has! Haha! Continuing on, on June 26, my 25th birthday, I work up with my period. I was absolutely devastated. I always thought I would have at least one child by the time I turned 25, and to find out yet again that I was not pregnant, was horrible.

So, we decided to do another cycle just like the last one, Femara, Ovidrel and IUI, my follicles didn't really grow very big on this cycle and there were only about 2 that were growing, but it only takes 1 to get pregnant. In the meantime, I met with Dr Sullivan to discuss what came next if this were to not work. Which as you can imagine, it did not.

So, here's what came next. Instead of taking an oral fertility medication, I would now only do injectibles. The medicine that the doctor put me on was Follistim. Follistim carries many benefits, but it also carries many risks. It's beneficial in that it grows the follicles faster, and bigger and people typically respond better to this if they didn't respond as well to the orals. Some of the risks are, our chance of multiples has now doubled, and hyper/over-stimulation can occur where in the most extreme cases, the ovaries blow up like balloons and if they become too full, they can burst! Eeekk! Follistim is administered via a pen. Every time a new shot is given, a new needle is attached and there is a dial that is adjusted to how much of the medicine the doctor wants the patient to have. Ohh and being on Follistim, the doctors monitor the patient much more closely via bloodwork and ultrasound every couple days. On Day 3, Follistim was started. This cycle, I drove to Buffalo 6 times which is approximately 120 miles each time. On Day 10, after I had been in for bloodwork that morning. I got a phone call from the Doctor (which the Nurses always make the calls, so I knew it had to be bad). He indicated that my estrogen had more than doubled since the previous day and that I was on the verge of being over-stimulated, so the cycle had to come to a halt! He specifically told me to "stay away from that husband of yours" because it'd be too dangerous to pursue the cycle. I had way too many follicles, which can result in way too many babies.

A very strange thing happened next, 7 days later on what would be cycle day 17, I began my cycle. Now I'm used to having cycles around 32 days, this was practically half that. I went in for my Day 3 ultrasound, and the nurse said I "have crazy ovaries going on" which is not something the doctors want to see on a day 3, on day 3, your ovaries should be nice and quiet. Another downside of the Follistim, the old follicles like to stick around from the previous cycle, we only want fresh new follicles for a new cycle. So, cure for this...take birth control for 2 weeks. Wait, now I've been trying to get pregnant now for over a year, and now I have to take birth control?! Not cool!! Well I did, so I was blessed with another period 18 days later.

Since I reacted "too well" by developing so many follicles after the Follistim last cycle, the doctor's decided to do a hybrid cycle basically. I go back to taking the Femara for days 3-7 to get the follicles growing, then on Day 7 I begin taking lower dosages of Follistim, while continuing to be monitored every couple of days to see how things are looking. By adding the Follistim to the Femara, the Follistim picks the couple growing follicles and grows them even bigger than they could grow with only Femara. On Day 15, they had me do the Ovidrel shot (which I did for the first time ever myself because I had to take the shot while I was at a Tupperware party, I'm really proud of myself for being able to do this). Then on Day 17, I had the IUI. I woke up that morning feeling like my stomach hurt. Well I get up to the doctor's office and the nurse asks how I'm feeling and I tell her about my little belly ache and she tells me those are my ovaries telling me they're "full" and ready for ovulation! Wow best belly ache ever! This was a great sign, I was so excited because I'd never felt this before. Before the IUI was done, an ultrasound is always done to look at the ovaries, and they looked great, best cycle I'd had thus far!

Well, all of a sudden last Sunday, October 2nd, I got crampy and started my cycle. This was very hard on me. I'm always hoping for the best but expecting the worst, but this time things were different. I reacted very well to the meds, I got the ovary ache, nurses were so hopeful...so it was so hard starting that cycle.

One of the options discussed in July was if the Follistim didn't work, then he wanted to do surgery. At this point, it's unexplained to the doctor why I can't get pregnant. I've had "help" for the majority of my cycles over the last year, and have tried lots of different things, on top of that I'm healthy, so in his eyes, I should have gotten pregnant by now.

So, next Friday October 14th, I'm having a Laparoscopy where a tiny camera will be inserted into my abdomen which will then will be used to look at my reproductive system. The doctor will be looking for scar tissue, endometriosis, anything that could suggest why I haven't gotten pregnant. If he finds nothing, I'm not sure what's next. If he does find something, it'll obviously depend on what he finds. This is considered to be a minimally invasive surgery, but it's still surgery, I have to have pre-op testing and be put under anesthesia. Casey will take off of work to bring me and I will probably be laid up all weekend, hopefully no more, but everyone handles things differently, the scarring with this should also be minimal.

So that's everything I can think of at 10:00pm on a Friday night (posted Saturday night because my computer decided to act up), this basically explains what Casey and I have been through over the last 15 months. It saddens me to see other people get pregnant. I'm happy for them, but at the same time I always wonder, why can't that be me? I do have Baby Envy and get sad a lot. There are many times where I feel like I'm failing. I feel like I've taken the right path in life, I have a Master's degree, a great job with amazing benefits, a supportive husband, I own my home, I feel we're financially ready for a child and yet I can't do the thing I'm supposed to do. As this goes on and on, I become more and more open because it does help to talk about it. I've found people to talk to and it has definitely helped me more. Anyways, that's it for now, I know it's long but oh well, my story is long. And now I'm going to bed to cuddle with my wonderful, supportive husband. Good night <3